EC HPLC column (analytical), NUCLEOSIL 100-10 CN, 10 µm, 250×4 mm

Description

The cyanopropyl phase is able to cause a clearly recognizable different retention behavior than purely alkyl-functionalized surface modifications. The polarity can be classified as intermediate based on several retention mechanisms such as dipole-dipole, π-π-π and also hydrophobic interactions. Therefore, CN phases show a pronounced selectivity for polar organic compounds as well as for molecules containing π electron systems (e.g. analytes with double bonds). This HPLC phase can be operated both in RP mode with aqueous-organic eluent mixtures and in NP mode, e.g. with hexane as the mobile phase. The HPLC column is packed with a CN modification based on the original NUCLEOSIL silica gel. This is one of the first spherical silica gels for HPLC and was developed by MACHEREY-NAGEL in 1974. It is manufactured exclusively in Germany and is still one of the most frequently used HPLC silica gels in quality control worldwide.